Selected Publications

2018

Diffuse microvascular dysfunction and loss of white matter integrity predict poor outcomes in patients with acute ischemic stroke.
Rost NS, Cougo P, Lorenzano S, Li H, Cloonan L, Bouts MJ, Lauer A, Etherton MR, Karadeli HH, Musolino PL, Copen WA, Arai K, Lo E, Feske S, Furie K, Wu O.
J Cereb Blood Flow Metab. 2018 Jan; 38(1): 75-86.

Direct vascular channels connect skull bone marrow and the brain surface enabling myeloid cell migration.
Herisson F, Frodermann V, Courties G, Rohde D, Sun Y, Vandoorne K, Wojtkiewicz GR, Masson GS, Vinegoni C, Kim J, Kim D, Weissleder R, Swirski FK, Moskowitz MA, Nahrendorf M.
Nature Neuroscience. 2018; 21: 1209–1217.

Oxidative Stress Biomarkers of Brain Damage: Hyperacute Plasma F2-Isoprostane Predicts Infarct Growth in Stroke.
Lorenzano S, Rost NS, Khan M, Li H, Lima FO, Maas MB, Green RE, Thankachan TK, Dipietro AJ, Arai K, Som AT, Pham LD, Wu O, Harris GJ, Lo EH, Blumberg JB, Milbury PE, Feske SK, Furie KL.
Neurology. 2018; 49(3): 630-637.

Posterior reversible encephalopathy syndrome in stroke-prone spontaneously hypertensive rats on high-salt diet.
Herisson F, Zhou I, Mawet J, Du E, Barfejani AH, Qin T, Cipolla MJ, Sun PZ, Rost NS, Ayata C.
J Cereb Blood Flow Metab. 2018; 271678X17752795.

In search of a putative imaging biomarker for Fabry disease: Go with the flow?
Giese AK, Rost NS.
Neurology. 2018; 90(16): 721-722.

2017

Design and Rationale for Examining Neuroimaging Genetics in Ischemic Stroke: the MRI-GENIE Study.
Giese AK, Schirmer MD, Donahue KL, Cloonan L, Irie R, Winzeck S, R. Irie, Bouts MJRJ, McIntosh EC, Mocking SJ, Dalca AV, Sridharan R, Xu H, Frid P, Giralt-Steinhauer E, Holmegaard L, Roquer J, Wasselius J, Cole JW, McArdle PF, Broderick JP, Jimenez-Conde J, Jern C, Kissela BM, Kleindorfer DO, Lemmens R, Lindgren A, Meschia JF, Rundek T, Sacco RL, Schmidt R, Sharma P, Slowik A, Thijs V, Woo D, Worrall BB, Kittner SJ, Mitchell BD, Rosand J, Golland P, Wu O, Rost NS.
Neurol Genet. 2017; 3: 2376-7839.

Diffuse microvascular dysfunction and loss of white matter integrity predict poor outcomes in patients with acute ischemic stroke.
Rost NS, Cougo P, Lorenzano S, Li H, Cloonan L, Bouts MJ, Lauer A, Etherton MR, Karadeli HH, Musolino PL, Copen WA, Arai K, Lo EH, Feske SK, Furie KL, Wu O.
J Cereb Blood Flow Metab. 2017; 271678X17706449.

Integrity of normal-appearing white matter and functional outcomes after acute ischemic stroke.
Etherton MR, Wu O, Cougo P, Giese AK, Cloonan L, Fitzpatrick KM, Kanakis AS, Boulouis G, Karadeli HH, Lauer A, Rosand J, Furie KL, Rost NS.
Neurology. 2017;88(18):1701-1708.

Infarct topography and functional outcomes.
Etherton MR, Rost NS, Wu O.
J Cereb Blood Flow Metab. 2017; 271678X17700666.

Structural Integrity of Normal Appearing White Matter and Sex-Specific Outcomes After Acute Ischemic Stroke.
Etherton MR, Wu O, Cougo P, Giese AK, Cloonan L, Fitzpatrick KM, Kanakis AS, Boulouis G, Karadeli HH, Lauer A, Rosand J, Furie KL, Rost NS.
Stroke. 2017; 48(12): 3387-3389.

ABCD1 dysfunction alters white matter microvascular perfusion.
Lauer A, Da X, Hansen MB, Boulouis G, Ou Y, Cai X, Liberato Celso Pedrotti A, Kalpathy-Cramer J, Caruso P, Hayden DL, Rost N, Mouridsen K, Eichler FS, Rosen B, Musolino PL.
Brain. 2017; 140(12): 3139-3152.

Population Based IMage Imputation.
Dalca AV, Bouman KL, Freeman WT, Rost NS, Sabuncu MR, Golland P.
Inf Process Med Imaging. 2017; 10265: 659-671.

2016

Patch-Based Discrete Registration of Clinical Brain Images.
Dalca AV, Bobu A, Rost NS, Golland P.
Patch Based Tech Med Imaging (2016). 2016;9993:60-67.

Recent Advances in Leukoaraiosis: White Matter Structural Integrity and Functional Outcomes after Acute Ischemic Stroke.
Etherton MR, Wu O, Rost NS.
Curr Cardiol Rep. 2016;18(12):123. Review.

Determinants of white matter hyperintensity burden in patients with Fabry disease.
Rost NS, Cloonan L, Kanakis AS, Fitzpatrick KM, Azzariti DR, Clarke V, Lourenco CM, Germain DP, Politei JM, Homola GA, Sommer C, Üçeyler N, Sims KB.
Neurology. 2016;86(20):1880-6.

Before 2016

Role of Acute Lesion Topography in Initial Ischemic Stroke Severity and Long-Term Functional Outcomes.
Wu O, Cloonan L, Mocking SJ, Bouts MJ, Copen WA, Cougo-Pinto PT, Fitzpatrick K, Kanakis A, Schaefer PW, Rosand J, Furie KL.
Stroke. 2015;46(9):2438-44.

Metabolic determinants of white matter hyperintensity burden in patients with ischemic stroke.
Cloonan L, Fitzpatrick KM, Kanakis AS, Furie KL, Rosand J, Rost NS.
Atherosclerosis. 2015;240(1):149-53.

Segmentation of cerebrovascular pathologies in stroke patients with spatial and shape priors.
Dalca AV, Sridharan R, Cloonan L, Fitzpatrick KM, Kanakis A, Furie KL, Rosand J, Wu O, Sabuncu M, Rost NS, Golland P.
Med Image Comput Comput Assist Interv. 2014;17(Pt 2):773-80.

Clinical neurogenetics: stroke.
Rost NS.
Neurol Clin. 2013;31(4):915-28.